锟斤拷锟绞拷亟锟斤拷锟�(Rheumatoid arthritis锟斤拷RA) 锟斤拷一锟街诧拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟皆硷拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟脚拷裕锟斤拷夜锟斤拷锟斤拷锟斤拷锟皆嘉� 0.32-0.36%锟斤拷锟斤拷要锟斤拷锟斤拷为锟皆筹拷锟皆★拷锟斤拷锟皆★拷锟斤拷锟斤拷锟皆讹拷亟锟斤拷住锟斤拷亟诨锟侥わ拷锟斤拷锟斤拷锟斤拷锟街拷锟斤拷锟斤拷锟斤拷锟斤拷纬锟窖拷锟斤拷瑁拷址锟斤拷亟锟斤拷锟斤拷恰锟斤拷锟斤拷锟斤拷鹿恰锟斤拷痛锟斤拷图锟斤拷锟饺ｏ拷锟斤拷晒亟锟斤拷锟斤拷恰锟斤拷呛凸亟锟斤拷锟斤拷苹锟斤拷锟斤拷锟斤拷盏锟斤拷鹿亟诨锟斤拷魏凸锟斤拷锟缴ナэ拷锟�
锟斤拷锟劫达拷锟斤拷锟街ｏ拷
1锟斤拷 症状锟斤拷锟斤拷锟斤拷
锟斤拷锟斤拷筒锟斤拷锟斤拷懈锟斤拷锟斤拷锟届，锟接讹拷锟捷★拷锟斤拷微锟斤拷锟劫关斤拷锟阶碉拷锟斤拷锟斤拷锟斤拷锟斤拷远锟截斤拷锟阶★拷锟斤拷锟桔关斤拷锟皆斤拷锟斤拷指锟斤拷亟凇锟斤拷锟街革拷亟凇锟斤拷锟斤拷狻拷纭⑾ワ拷锟斤拷锟街猴拷亟锟斤拷锟轿拷锟斤拷锟斤拷锟斤拷椎锟斤拷锟斤拷亟凇锟斤拷锟斤拷锟斤拷图锟斤拷锟斤拷亟锟揭诧拷锟斤拷锟斤拷郏锟斤拷锟斤拷锟筋动锟斤拷锟睫ｏ拷锟脚关斤拷锟斤拷锟斤拷锟劫硷拷锟斤拷锟截斤拷锟阶筹拷锟斤拷锟斤拷为锟皆筹拷锟皆★拷锟斤拷锟斤拷锟斤拷锟斤拷锟酵猴拷压痛锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷1小时锟斤拷锟斤拷 锟斤拷锟斤拷为锟斤拷锟斤拷锟侥关节伙拷锟斤拷锟斤拷锟斤拷锟斤拷锟截斤拷强直锟斤拷锟斤拷指锟截节的帮拷锟斤拷位锟斤拷锟斤拷指锟斤拷卟锟狡憋拷统省锟斤拷锟届颈锟斤拷锟斤拷锟斤拷钮锟阶伙拷锟斤拷锟斤拷锟街★拷锟斤拷症锟斤拷锟竭关节筹拷锟斤拷维锟皆伙拷锟斤拷锟角恐憋拷锟斤拷锟斤拷锟截斤拷锟斤拷围锟斤拷锟斤拷萎锟斤拷锟斤拷锟斤拷锟斤拷失去锟截节癸拷锟杰ｏ拷锟斤拷使锟斤拷锟筋不锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟截斤拷症状锟解，锟斤拷锟缴筹拷锟街关斤拷锟斤拷锟斤拷锟斤拷锟�
锟金害ｏ拷锟斤拷锟斤拷锟绞拷锟节ｏ拷锟侥★拷锟轿★拷锟斤拷锟斤拷锟斤拷围锟今经硷拷锟桔等诧拷锟戒。
2锟斤拷 实锟斤拷锟斤拷
锟斤拷锟斤拷锟筋动锟节伙拷锟斤拷锟斤拷锟斤拷锟斤拷锟叫讹拷锟斤拷细锟斤拷锟斤拷色锟斤拷锟斤拷贫血锟斤拷锟斤拷细锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟绞憋拷杉锟斤拷锟斤拷锟斤拷锟斤拷锟较革拷锟斤拷锟窖★拷锟斤拷锟斤拷啵拷锟斤拷锟斤拷锟斤拷虻鞍锟絀gG锟斤拷IgM锟斤拷IgA锟斤拷锟斤拷锟竭ｏ拷血锟藉补锟斤拷水平锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷撸锟�60%锟斤拷80%锟斤拷锟斤拷锟叫革拷水平锟斤拷锟绞拷锟斤拷樱锟絉F锟斤拷锟斤拷锟斤拷RF锟斤拷锟斤拷也锟斤拷锟斤拷锟斤拷锟皆革拷染锟斤拷锟斤拷锟阶★拷锟斤拷说龋锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷织锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟剿★拷锟斤拷锟斤拷锟界抗锟斤拷锟绞碉拷锟阶匡拷锟藉（AKA锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟接ｏ拷APF锟斤拷锟酵匡拷锟斤拷锟较帮拷锟斤拷锟斤拷模锟紺CP锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷湿锟截斤拷锟阶碉拷锟斤拷锟斤拷薪细叩锟斤拷锟斤拷锟斤拷锟斤拷锟皆ｏ拷锟斤拷锟斤拷锟斤拷锟皆斤拷锟斤拷30%锟斤拷锟揭★拷
3锟斤拷 X锟竭硷拷锟�
为锟斤拷确锟斤拷锟斤拷锟斤拷锟斤拷稀锟斤拷锟斤拷诤头锟秸癸拷锟斤拷锟斤拷锟节诧拷锟斤拷应锟斤拷锟斤拷锟剿拷锟截节猴拷锟街硷拷锟斤拷锟斤拷双锟斤拷X锟斤拷片锟斤拷锟皆硷拷锟斤拷锟斤拷锟斤拷锟桔关节碉拷X锟斤拷片锟斤拷RA锟斤拷X锟斤拷片锟斤拷锟节憋拷锟斤拷为锟截斤拷锟斤拷围锟斤拷锟斤拷织锟斤拷锟酵ｏ拷锟截节革拷锟斤拷锟斤拷裙锟斤拷锟斤拷锟斤拷桑锟斤拷锟街拷锟斤拷止亟诩锟较讹拷锟秸拷锟斤拷亟锟斤拷苹锟斤拷锟斤拷亟锟斤拷锟轿伙拷锟斤拷诤稀锟斤拷锟斤拷莨亟锟斤拷苹锟斤拷潭冉锟絏锟竭改憋拷锟轿拷锟斤拷冢锟斤拷锟�1锟斤拷
锟斤拷1 锟斤拷 锟斤拷锟绞拷亟锟斤拷锟絏锟竭斤拷展锟侥凤拷锟斤拷
I锟节ｏ拷 锟斤拷锟斤拷锟节ｏ拷
1*锟斤拷X锟竭硷拷锟斤拷锟斤拷苹锟斤拷愿谋锟�
2锟斤拷锟斤拷锟缴硷拷锟斤拷锟斤拷锟斤拷锟斤拷
II锟节ｏ拷锟斤拷锟斤拷锟节ｏ拷
1*锟斤拷锟斤拷锟斤拷锟斤拷锟缴ｏ拷锟斤拷锟斤拷锟斤拷鹊锟斤拷锟斤拷锟斤拷苹锟斤拷锟斤拷谢锟矫伙拷锟斤拷锟饺碉拷锟斤拷锟斤拷锟铰癸拷锟斤拷锟狡伙拷
2*锟斤拷锟缴硷拷锟截节活动锟斤拷锟睫ｏ拷锟斤拷锟睫关节伙拷锟斤拷
3锟斤拷锟斤拷锟节斤拷锟斤拷锟斤拷萎锟斤拷
4锟斤拷 锟叫关斤拷锟斤拷锟斤拷锟斤拷织锟斤拷锟斤拷锟斤拷锟节猴拷锟斤拷锟斤拷锟斤拷
III锟节ｏ拷锟斤拷锟斤拷锟节ｏ拷
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2*锟斤拷锟截节伙拷锟轿ｏ拷锟斤拷锟斤拷锟轿伙拷锟斤拷卟锟狡憋拷锟斤拷锟斤拷锟轿拷曰锟斤拷锟斤拷强直
3锟斤拷 锟姐泛锟侥硷拷萎锟斤拷
4锟斤拷锟斤拷锟叫关斤拷锟斤拷锟斤拷锟斤拷织锟斤拷锟斤拷锟斤拷锟节伙拷锟斤拷锟斤拷锟斤拷
IV锟节ｏ拷末锟节ｏ拷
1*锟斤拷锟斤拷维锟皆伙拷锟斤拷锟角恐�
2锟斤拷 III锟节憋拷准锟节革拷锟斤拷
锟斤拷准前锟斤拷锟斤拷*锟斤拷锟斤拷为锟斤拷锟节凤拷锟斤拷谋乇锟斤拷锟斤拷锟�
锟斤拷锟斤拷锟揭拷锟斤拷
1锟斤拷锟斤拷媳锟阶�
锟斤拷锟绞拷亟锟斤拷椎锟斤拷锟斤拷锟斤拷要锟斤拷锟斤拷锟劫达拷锟斤拷锟街★拷锟斤拷锟斤拷锟斤拷锟藉及X锟竭改变。锟斤拷锟酵的诧拷锟斤拷锟斤拷1987锟斤拷锟斤拷锟斤拷锟斤拷湿锟斤拷学学锟斤拷锟斤拷锟斤拷准锟斤拷锟斤拷2锟斤拷锟斤拷喜锟斤拷锟斤拷锟斤拷眩锟斤拷锟斤拷缘锟斤拷亟锟斤拷锟轿拷追锟街⒆达拷锟侥承╋拷锟斤拷锟斤拷汀锟斤拷锟斤拷锟斤拷锟斤拷湿锟截斤拷锟阶ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷锟铰╋拷铩ｏ拷锟斤拷锟叫╋拷锟斤拷撸锟斤拷锟斤拷锟窖拷锟斤拷虺９妗⒀拷锟斤拷锟紺锟斤拷应锟斤拷锟阶★拷锟斤拷锟绞拷锟斤拷拥燃锟斤拷锟解，锟斤拷锟斤拷锟斤拷锟剿磁癸拷锟斤拷锟斤拷锟斤拷MRI锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷稀锟斤拷钥锟斤拷锟斤拷锟斤拷湿锟截斤拷锟阶伙拷锟斤拷要锟斤拷锟节革拷锟介、锟斤拷锟斤拷锟斤拷谩锟�
2锟斤拷锟筋动锟斤拷锟叫讹拷
锟叫讹拷锟斤拷锟绞拷亟锟斤拷谆疃拷缘锟斤拷锟侥匡拷锟斤拷锟狡ｏ拷偷锟斤拷锟斤拷锟斤拷浴锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟绞憋拷洹拷亟锟斤拷锟酵达拷锟斤拷锟斤拷偷某潭取锟斤拷亟锟窖雇达拷锟斤拷锟斤拷偷锟斤拷锟侥匡拷锟斤拷亟诠锟斤拷锟斤拷锟斤拷锟斤拷瞥潭龋锟斤拷约锟斤拷锟斤拷锟斤拷锟街⒅革拷辏拷锟窖拷锟斤拷锟斤拷梅锟接︼拷锟斤拷缀锟窖★拷澹╋拷取锟�
3锟斤拷锟斤拷锟斤拷锟阶�
锟斤拷锟绞拷亟锟斤拷锟斤拷俅锟斤拷锟斤拷锟斤拷准锟斤拷 锟斤拷 锟斤拷锟斤拷时锟斤拷锟斤拷锟�15锟斤拷锟接ｏ拷锟斤拷 锟斤拷疲锟酵感ｏ拷锟斤拷 锟睫关斤拷痛锟斤拷锟斤拷 锟筋动时锟睫关斤拷痛锟斤拷亟锟斤拷锟窖雇达拷锟斤拷锟斤拷锟� 锟截节伙拷锟斤拷锟斤拷锟斤拷锟酵ｏ拷锟斤拷 血锟斤拷锟斤拷魏锟较凤拷锟斤拷女锟斤拷小锟斤拷30mm锟斤拷小时锟斤拷锟斤拷锟斤拷小锟斤拷20mm锟斤拷小时锟斤拷
锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟较诧拷锟斤拷锟斤拷锟斤拷锟斤拷2锟斤拷锟斤拷锟竭匡拷锟斤拷为锟劫达拷锟斤拷锟解；锟叫活动锟斤拷血锟斤拷锟阶★拷锟侥帮拷锟阶★拷锟斤拷膜锟阶★拷锟斤拷锟阶和斤拷锟斤拷锟斤拷原锟斤拷锟斤拷锟斤拷锟斤拷陆锟斤拷锟斤拷龋锟斤拷锟斤拷锟斤拷锟轿拷锟斤拷狻�
锟斤拷2锟斤拷 1987锟斤拷锟斤拷锟斤拷锟斤拷湿锟斤拷学学锟结（ARA锟斤拷锟斤拷锟绞拷亟锟斤拷追锟斤拷锟斤拷准
锟斤拷锟斤拷 锟斤拷 注锟斤拷锟斤拷锟斤拷锟斤拷
1. 锟斤拷锟斤拷 锟截节硷拷锟斤拷锟斤拷围锟斤拷硬锟斤拷锟斤拷锟劫筹拷锟斤拷1小时锟斤拷锟斤拷锟教★拷6锟杰ｏ拷
2. 3锟斤拷锟斤拷3锟斤拷锟斤拷锟斤拷锟斤拷锟较关节诧拷位锟侥关斤拷锟斤拷 医锟斤拷锟桔察到锟斤拷锟斤拷14锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟揭诧拷慕锟斤拷锟街革拷锟截节★拷锟斤拷指锟截节★拷锟斤拷锟解、膝锟斤拷锟阶硷拷锟斤拷趾锟截节ｏ拷锟斤拷锟桔硷拷3锟斤拷锟斤拷锟斤拷同时锟斤拷锟斤拷织锟斤拷锟酵伙拷锟揭�(锟斤拷锟角碉拷锟斤拷锟斤拷隆锟斤拷) (锟斤拷锟教★拷6锟斤拷)
3. 锟街关斤拷锟斤拷 锟斤拷锟斤拷指锟斤拷锟斤拷锟街革拷锟截斤拷锟斤拷锟叫ｏ拷锟斤拷锟斤拷锟斤拷一锟斤拷锟截斤拷锟斤拷锟斤拷 (锟斤拷锟教★拷6锟斤拷)
4. 锟皆筹拷锟皆关斤拷锟斤拷 锟斤拷锟斤拷亟锟酵憋拷锟斤拷锟�(双锟斤拷锟斤拷锟街革拷锟截节★拷锟斤拷指锟截节硷拷锟斤拷趾锟截斤拷锟斤拷锟斤拷时锟斤拷锟斤拷一锟斤拷锟斤拷锟皆对筹拷) (锟斤拷锟教★拷6锟斤拷)
5. 锟斤拷锟绞拷锟斤拷 医锟斤拷锟桔察到锟节癸拷突锟斤拷位锟斤拷锟届肌锟斤拷锟斤拷锟截斤拷锟斤拷围锟斤拷皮锟铰斤拷锟�
6. 锟斤拷锟绞拷锟斤拷锟斤拷锟斤拷锟� 锟轿何硷拷夥斤拷锟街わ拷锟窖拷锟斤拷锟斤拷湿锟斤拷锟接猴拷锟斤拷锟届常锟斤拷锟斤拷锟矫凤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷群锟叫碉拷锟斤拷锟斤拷锟斤拷小锟斤拷5锟斤拷
7. 锟斤拷锟斤拷学锟侥憋拷 锟斤拷锟街猴拷锟斤拷暮锟角拔伙拷锟斤拷锟斤拷械锟斤拷偷锟斤拷锟斤拷湿锟截斤拷锟阶凤拷锟斤拷学锟侥变：锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟绞达拷锟斤拷锟斤拷酃亟诩锟斤拷锟斤拷诮锟斤拷锟轿伙拷锟斤拷锟饺凤拷墓锟斤拷锟斤拷迅锟�
锟斤拷锟斤拷7锟斤拷锟斤拷锟斤拷4锟斤拷锟斤拷4锟斤拷锟斤拷锟较诧拷锟脚筹拷锟斤拷锟斤拷锟截斤拷锟阶硷拷锟斤拷锟斤拷锟斤拷锟斤拷湿锟截斤拷锟斤拷
4锟斤拷 锟斤拷锟斤拷锟斤拷锟�
锟斤拷锟斤拷锟绞拷亟锟斤拷椎锟斤拷锟较癸拷锟斤拷锟叫ｏ拷应注锟斤拷锟斤拷枪亟锟斤拷住锟酵达拷锟斤拷怨亟锟斤拷住锟斤拷锟接︼拷怨亟锟斤拷住锟斤拷锟叫硷拷锟斤拷亟锟斤拷缀锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷织锟斤拷锟斤拷系统锟皆猴拷锟斤拷谴锟斤拷锟斤拷锟斤拷锟斤拷酆锟斤拷锟斤拷锟接财わ拷锟斤拷龋锟斤拷锟斤拷碌墓亟锟斤拷锟斤拷锟斤拷锟斤拷
锟斤拷1锟斤拷锟角关斤拷锟阶ｏ拷锟斤拷 锟矫诧拷为锟斤拷锟斤拷锟皆骨关节诧拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟�40锟斤拷锟斤拷锟较ｏ拷锟斤拷要锟桔硷拷膝锟斤拷锟斤拷锟斤拷锟饺革拷锟截关节★拷锟筋动时锟截斤拷痛锟斤拷锟截ｏ拷锟斤拷锟叫关斤拷锟斤拷锟酵★拷锟斤拷液锟斤拷锟斤拷指锟角关斤拷锟阶筹拷锟斤拷锟斤拷锟斤拷为锟斤拷锟绞拷亟锟斤拷祝锟斤拷锟斤拷锟斤拷锟皆讹拷锟街革拷锟截节筹拷锟街赫诧拷锟角ｏ拷Heberden锟斤拷锟斤拷诤徒锟斤拷锟街革拷亟诔锟斤拷植锟斤拷亩锟斤拷锟紹ouchard锟斤拷锟斤拷锟绞憋拷妆锟斤拷锟轿拷锟侥わ拷住锟斤拷枪亟锟斤拷锟酵拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟酵达拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷血锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟绞拷锟斤拷锟斤拷锟斤拷曰锟酵滴讹拷锟斤拷锟皆★拷X锟斤拷示锟截节硷拷隙锟斤拷窄锟斤拷锟截节憋拷缘锟绞达拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷纬伞锟�
锟斤拷2锟斤拷痛锟界锟斤拷 锟斤拷锟斤拷痛锟斤拷锟皆关斤拷锟斤拷锟斤拷时锟斤拷锟斤拷锟绞拷亟锟斤拷锟斤拷锟斤拷疲锟酵达拷锟斤拷怨亟锟斤拷锥锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟皆ｏ拷锟斤拷锟绞凤拷锟斤拷锟斤拷锟斤拷锟斤拷锟矫凤拷锟斤拷位为锟斤拷锟斤拷锟揭伙拷锟街猴拷亟诨锟斤拷乒亟冢锟揭诧拷锟斤拷址锟较ワ拷锟斤拷住锟斤拷狻拷锟斤拷止亟冢锟斤拷锟斤拷苑锟斤拷锟绞蓖拷锟窖拷锟斤拷锟剿斤拷锟斤拷撸锟斤拷锟斤拷锟酵达拷锟斤拷怨亟锟斤拷卓锟斤拷诠亟诤投锟斤拷锟斤拷炔锟轿伙拷锟斤拷锟酵达拷锟绞拷锟�
锟斤拷3锟斤拷锟斤拷屑锟斤拷锟截斤拷锟阶ｏ拷锟斤拷锟斤拷屑锟斤拷锟截斤拷锟斤拷锟斤拷锟斤拷指锟斤拷锟斤拷趾远锟剿关斤拷锟斤拷锟斤拷为锟斤拷锟斤拷也锟缴筹拷锟街关节伙拷锟轿ｏ拷锟斤拷锟斤拷锟绞拷锟斤拷锟斤拷锟斤拷裕锟斤拷野锟斤拷锟斤拷锟叫硷拷锟斤拷锟狡わ拷锟斤拷锟街革拷撞锟斤拷洹�
锟斤拷4锟斤拷强直锟皆硷拷锟斤拷锟阶ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷要锟街凤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷围锟截斤拷也锟斤拷锟斤拷锟桔ｏ拷锟截憋拷锟斤拷锟斤拷膝锟斤拷锟阶★拷锟脚关斤拷为锟阶凤拷症状锟竭ｏ拷锟斤拷锟斤拷锟斤拷锟绞拷亟锟斤拷锟斤拷锟斤拷锟金。该诧拷锟斤拷锟斤拷锟斤拷锟截碉拷锟斤拷锟斤拷锟斤拷锟斤拷远锟斤拷锟斤拷锟斤拷锟斤拷要锟街凤拷锟斤拷锟侥关节硷拷锟斤拷锟斤拷锟斤拷锟斤拷锟杰关斤拷锟斤拷锟桔讹拷锟斤拷锟斤拷肢锟斤拷锟皆称关斤拷锟斤拷锟斤拷为锟斤拷锟斤拷锟斤拷锟叫硷拷锟斤拷锟斤拷祝锟斤拷锟�90-95%锟斤拷锟斤拷HLA锟斤拷B27锟斤拷锟皆ｏ拷锟斤拷锟斤拷锟绞拷锟斤拷锟斤拷锟斤拷裕锟斤拷锟斤拷锟斤拷墓亟诩锟斤拷锟斤拷锟斤拷锟絏锟竭改憋拷锟斤拷锟较硷拷锟叫帮拷锟斤拷锟斤拷
锟斤拷5锟斤拷锟斤拷锟斤拷锟街拷锟斤拷锟斤拷碌墓亟锟斤拷祝锟斤拷锟� 锟斤拷锟斤拷锟桔猴拷锟斤拷锟斤拷系统锟皆猴拷锟斤拷谴锟斤拷锟斤拷锟斤拷泄亟锟街⒆达拷锟斤拷也锟斤拷只锟斤拷锟斤拷锟斤拷湿锟斤拷锟斤拷锟斤拷锟皆ｏ拷锟斤拷锟斤拷锟角讹拷锟斤拷锟斤拷应锟斤拷锟斤拷锟斤拷锟斤拷锟劫达拷锟斤拷锟街猴拷锟斤拷锟斤拷锟斤拷锟藉。
锟斤拷6锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷 锟皆诧拷锟斤拷锟酵碉拷锟皆碉拷锟斤拷锟斤拷锟劫关斤拷锟金病碉拷锟斤拷锟绞拷亟锟斤拷锟揭拷锟斤拷染锟皆关斤拷锟阶ｏ拷锟斤拷锟斤拷锟斤拷烁锟饺撅拷锟斤拷锟斤拷锟接︼拷怨亟锟斤拷缀头锟绞拷锟斤拷锟斤拷锟斤拷
[锟斤拷锟狡凤拷锟斤拷]
目前锟斤拷锟斤拷锟绞拷亟锟斤拷椎锟斤拷锟斤拷瓢锟斤拷锟揭╋拷锟斤拷锟斤拷啤锟斤拷锟斤拷锟斤拷锟狡猴拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟狡等★拷
1锟斤拷 药锟斤拷锟斤拷锟斤拷
锟斤拷前锟斤拷锟斤拷锟斤拷应锟矫碉拷药锟斤，锟皆硷拷植锟斤拷药锟斤拷锟斤拷锟斤拷锟斤拷全锟斤拷锟狡关斤拷锟狡伙拷锟斤拷锟斤拷只锟杰伙拷锟斤拷锟斤拷痛锟斤拷锟斤拷锟斤拷锟斤拷踊锟斤拷锟街拷姆锟秸癸拷锟斤拷锟斤拷锟斤拷锟斤拷湿锟截斤拷锟阶的筹拷锟斤拷药锟斤拷锟轿拷拇锟斤拷啵拷锟斤拷锟斤拷锟斤拷嗫癸拷锟揭╋拷锟絅SAIDs锟斤拷锟斤拷锟斤拷锟狡诧拷锟斤拷目锟斤拷锟绞╋拷锟紻MARDs锟斤拷锟斤拷锟斤拷皮锟绞硷拷锟截猴拷植锟斤拷药锟斤拷
锟斤拷 NSAIDs锟斤拷锟斤拷通锟斤拷锟斤拷锟狡伙拷锟斤拷锟斤拷锟斤拷酶锟斤拷锟皆ｏ拷锟斤拷锟斤拷前锟斤拷锟斤拷锟截合成讹拷锟斤拷锟叫匡拷锟阶★拷止痛锟斤拷锟斤拷锟饺★拷锟斤拷锟斤拷锟斤拷锟矫★拷锟斤拷锟斤拷NSAIDs使前锟斤拷锟斤拷锟截的合成硷拷锟劫ｏ拷锟绞可筹拷锟斤拷锟斤拷应锟侥诧拷锟斤拷锟斤拷应锟斤拷锟斤拷胃锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷应锟斤拷锟斤拷锟侥★拷呕锟铰★拷锟斤拷痛锟斤拷锟斤拷泻锟斤拷锟斤拷锟酵★拷食锟斤拷锟斤拷锟窖ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟今、筹拷血锟斤拷锟斤拷锟阶等ｏ拷锟斤拷锟洁不锟斤拷锟斤拷应锟斤拷锟斤拷锟斤拷注锟斤拷锟斤拷锟劫ｏ拷锟斤拷锟斤拷水锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷血锟截★拷血锟津、碉拷锟斤拷锟津、硷拷锟斤拷锟斤拷锟斤拷锟阶ｏ拷锟斤拷锟斤拷锟竭凤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟杰诧拷全锟斤拷NSAIDs锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷血细锟斤拷锟斤拷锟劫★拷锟斤拷血锟较帮拷锟斤拷锟斤拷锟斤拷锟较帮拷锟斤拷贫血锟斤拷锟轿癸拷锟金害等ｏ拷锟斤拷锟斤拷锟斤拷锟竭凤拷锟斤拷锟斤拷锟斤拷锟斤拷应锟斤拷皮锟筋、锟斤拷锟斤拷锟斤拷锟斤拷锟皆硷拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟铰斤拷锟斤拷锟睫撅拷锟斤拷锟斤拷膜锟阶等★拷锟斤拷锟斤拷锟斤拷锟�
湿锟截斤拷锟阶的筹拷锟斤拷NSAIDs锟斤拷锟斤拷锟斤拷3锟斤拷
锟斤拷3锟斤拷 锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟绞拷亟锟斤拷椎锟絅SAIDs
锟斤拷锟斤拷 英锟斤拷 锟斤拷衰锟斤拷(小时) 每锟斤拷锟杰硷拷锟斤拷mg锟斤拷 每锟轿硷拷锟斤拷锟斤拷mg锟斤拷 锟斤拷/锟斤拷
锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷
锟斤拷锟斤拷锟� ibuprofen 2 1200-3200 400-600 3-4
锟斤拷锟斤拷锟斤拷 naproxen 14 500-1000 250-500 2
锟斤拷锟斤拷锟斤拷锟� loxoprofen 1.2 180 60 3
锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷
双锟饺凤拷锟斤拷 diclofenac 2 75-150 25-50 3-4
锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷
锟斤拷锟斤拷锟斤拷锟斤拷 indometacin 3-11 75 25 3
锟斤拷锟斤拷锟斤拷 sulindac 18 400 200 2
锟斤拷锟斤拷锟斤拷锟斤拷 acemetacin 3 90-180 30-60 3
锟斤拷锟斤拷锟斤拷锟斤拷锟�
锟斤拷锟叫讹拷锟斤拷 etodolac 锟斤拷锟斤拷锟斤拷 8.3 400-1000 400-1000 1
锟斤拷锟斤拷锟斤拷锟斤拷
锟斤拷锟斤拷锟斤拷酮 nabumetone 锟斤拷锟斤拷锟斤拷锟斤拷24 1000-2000 1000 1-2
锟斤拷锟斤拷锟斤拷
锟斤拷痛锟斤拷锟斤拷 piroxicam 锟斤拷锟斤拷锟斤拷30-86 20 20 1
烯锟斤拷锟斤拷锟斤拷
锟斤拷锟斤拷锟斤拷锟斤拷 meloxicam 锟斤拷锟斤拷锟斤拷锟斤拷20 15 7.5-15 1
锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷
锟斤拷锟斤拷锟斤拷锟斤拷 nimesulide 2-5 400 100-200 2
锟斤拷锟斤拷锟斤拷
锟斤拷锟斤拷锟斤拷锟斤拷 celecoxib 11 200-400 100-200 1-2
锟睫凤拷锟斤拷锟斤拷 rofecoxib 17 12.5-25 12.5-25 1
锟斤拷锟斤拷锟斤拷锟斤拷锟叫撅拷锟斤拷锟街伙拷锟斤拷锟斤拷酶锟斤拷锟斤拷锟斤拷同锟斤拷锟届构锟藉，锟斤拷锟斤拷锟斤拷锟斤拷酶-1锟斤拷COX-1锟斤拷锟酵伙拷锟斤拷锟斤拷酶-2(COX-2)锟斤拷选锟斤拷锟斤拷COX-2锟斤拷锟狡硷拷锟斤拷锟斤拷锟斤拷锟斤拷锟洁）锟斤拷锟窖★拷锟斤拷缘拇锟酵砃SAIDs锟斤拷龋锟斤拷锟斤拷锟斤拷约锟斤拷锟斤拷锟斤拷锟轿革拷锟斤拷锟斤拷锟斤拷锟斤拷锟接︼拷锟� 锟斤拷锟斤拷指锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷选锟斤拷锟斤拷锟絅SAIDs锟斤拷锟斤拷锟斤拷锟斤拷应锟斤拷锟藉化锟斤拷只锟斤拷锟斤拷一锟斤拷NSAIDs锟斤拷锟斤拷使锟斤拷1锟斤拷2锟杰猴拷锟斤拷效锟脚革拷锟斤拷为锟斤拷一锟街ｏ拷锟斤拷锟斤拷锟斤拷锟街伙拷锟斤拷锟斤拷锟斤拷锟斤拷NSAIDs同时锟斤拷锟矫ｏ拷锟斤拷锟斤拷锟斤拷效锟斤拷锟斤拷锟接ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷应锟斤拷锟洁；锟斤拷锟斤拷锟斤拷锟斤拷选锟矫帮拷衰锟节短碉拷NSAIDs药锟斤，锟斤拷锟斤拷锟斤拷锟斤拷史锟斤拷锟斤拷锟斤拷锟剿ｏ拷锟剿凤拷锟斤拷选锟斤拷锟斤拷COX-2锟斤拷锟狡硷拷锟皆硷拷锟斤拷胃锟斤拷锟斤拷锟侥诧拷锟斤拷锟斤拷应锟斤拷应强锟斤拷锟斤拷NSAIDs锟斤拷锟杰硷拷锟斤拷锟斤拷锟绞拷亟锟斤拷椎锟街⒆达拷锟斤拷锟斤拷锟斤拷芨谋洳★拷毯锟皆わ拷锟斤拷亟锟斤拷苹锟�,锟绞憋拷锟斤拷锟斤拷DMARDs锟斤拷锟斤拷应锟矫★拷
锟斤拷 DMARDs锟斤拷锟斤拷锟斤拷锟斤拷药锟斤拷锟絅SAIDs锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟劫达拷症状锟斤拷锟斤拷锟皆革拷锟狡达拷约锟斤拷1-6锟斤拷锟铰ｏ拷锟斤拷锟街筹拷锟斤拷锟斤拷锟斤拷药锟斤拷锟斤拷锟戒不锟竭憋拷锟斤拷锟斤拷止痛锟酵匡拷锟斤拷锟斤拷锟矫ｏ拷锟斤拷锟叫革拷锟狡猴拷锟接伙拷锟斤拷锟斤拷锟秸癸拷锟斤拷锟斤拷谩锟侥壳帮拷胁锟斤拷锟斤拷锟斤拷锟绞拷亟锟斤拷椎锟斤拷锟斤拷锟斤拷锟窖★拷锟斤拷锟紻MARDs锟斤拷锟斤拷锟斤拷效锟酵凤拷锟矫等匡拷锟角ｏ拷一锟斤拷锟斤拷选锟阶帮拷锟斤拷锟绞ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷为锟斤拷锟斤拷锟斤拷锟狡的伙拷锟斤拷药锟斤。锟斤拷锟斤拷锟斤拷锟斤拷锟绞拷亟锟斤拷椎锟紻MARDs锟斤拷锟斤拷锟斤拷4锟斤拷
锟斤拷4锟斤拷 锟斤拷锟绞拷亟锟斤拷壮锟斤拷锟紻MARDs
药锟斤拷 锟斤拷效时锟斤拷(锟斤拷锟斤拷) 锟斤拷锟矫硷拷锟斤拷(mg) 锟斤拷药途锟斤拷 锟斤拷锟皆凤拷应
锟阶帮拷锟斤拷锟斤拷 1-2 7.5~15锟斤拷锟斤拷每锟斤拷 锟节凤拷锟斤拷注锟斤拷注 胃锟斤拷锟斤拷症状锟斤拷锟斤拷腔锟阶★拷皮锟筋、锟窖凤拷锟斤拷偶锟叫癸拷锟斤拷锟斤拷锟狡★拷锟斤拷锟洁毒锟皆ｏ拷锟轿硷拷锟绞变（锟斤拷锟斤拷锟斤拷锟斤拷锟截ｏ拷锟斤拷锟斤拷危锟斤拷锟斤拷锟斤拷锟斤拷
锟斤拷锟斤拷锟斤拷锟斤拷锟� 1-2 1000锟斤拷2~3锟斤拷/锟斤拷 锟节凤拷 皮锟筋，偶锟叫癸拷锟斤拷锟斤拷锟狡★拷胃锟斤拷锟斤拷锟斤拷锟斤拷锟杰★拷锟皆磺帮拷锟斤拷锟斤拷锟竭诧拷锟剿凤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷 1-2 10~20锟斤拷锟斤拷1锟斤拷/锟斤拷 锟节凤拷 锟斤拷泻锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷转锟斤拷酶锟斤拷锟竭ｏ拷锟窖凤拷锟斤拷皮锟斤拷
锟斤拷锟� 2-4 250锟斤拷锟斤拷锟斤拷1锟斤拷/锟斤拷 锟节凤拷 头锟轿★拷头痛锟斤拷皮锟筋、锟斤拷锟斤拷膜锟斤拷锟皆★拷偶锟斤拷锟侥硷拷锟金害ｏ拷锟斤拷锟斤拷锟斤拷窦房锟结功锟杰诧拷全锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟� 2-4 200锟斤拷锟斤拷 1~2锟斤拷/锟斤拷 锟节凤拷 偶锟斤拷皮锟筋、锟斤拷泻锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷膜锟斤拷锟皆ｏ拷锟斤拷锟斤拷锟斤拷窦房锟结功锟杰诧拷全锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟竭斤拷诺锟斤拷 4-6 3锟斤拷锟斤拷锟斤拷锟斤拷 1~2锟斤拷/锟斤拷 锟节凤拷 锟斤拷锟叫匡拷腔锟阶★拷皮锟筋、锟斤拷锟斤拷锟斤拷锟狡★拷血小锟斤拷锟斤拷佟锟斤拷锟斤拷锟斤拷颍锟斤拷锟斤拷锟斤拷实停锟斤拷锟叫猴拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟� 2-3 50~150锟斤拷 1锟斤拷/锟斤拷 锟节凤拷 锟斤拷锟斤拷锟斤拷锟狡★拷偶锟叫肝讹拷锟皆★拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷症状锟斤拷锟界发锟饺★拷胃锟斤拷锟斤拷症状锟斤拷锟轿癸拷锟斤拷锟届常锟斤拷锟斤拷霉锟斤拷 3-6 250~750锟斤拷 1锟斤拷/锟斤拷 锟节凤拷 皮锟筋、锟斤拷腔锟阶★拷味锟斤拷锟较帮拷锟斤拷锟斤拷锟斤拷锟津、癸拷锟斤拷锟斤拷锟狡★拷偶锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟竭诧拷
锟斤拷 锟阶帮拷锟斤拷锟绞ｏ拷methotrexate,锟斤拷MTX锟斤拷锟节凤拷锟斤拷锟斤拷注锟斤拷注锟斤拷锟斤拷效锟斤拷锟节凤拷60%锟斤拷锟秸ｏ拷每锟秸革拷药锟缴碉拷锟斤拷锟斤拷锟皆的癸拷锟斤拷锟斤拷锟狡和讹拷锟斤拷锟斤拷锟矫ｏ拷锟绞讹拷锟斤拷锟矫匡拷锟揭伙拷胃锟揭╋拷锟斤拷锟斤拷眉锟斤拷锟轿�7.5~25mg/锟杰ｏ拷锟斤拷锟斤拷锟斤拷症锟斤拷锟竭匡拷锟斤拷锟斤拷锟斤拷哟锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟侥诧拷锟斤拷锟斤拷应锟叫讹拷锟侥★拷锟斤拷锟阶★拷锟斤拷泻锟斤拷锟窖凤拷锟斤拷皮锟筋，锟斤拷锟斤拷锟斤拷锟街癸拷锟斤拷锟斤拷锟狡ｏ拷锟斤拷锟斤拷锟金害和肺硷拷锟绞变。也锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷胎锟斤拷影锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷药锟节间，应锟斤拷锟节诧拷血锟斤拷锟斤拷透喂锟斤拷堋锟�
锟斤拷 锟斤拷锟斤拷锟斤拷锟斤拷啶ｏ拷sulfasalazine,锟斤拷SSZ锟斤拷一锟斤拷锟斤拷锟�4~8锟杰猴拷锟斤拷效锟斤拷锟斤拷小锟斤拷锟斤拷锟金渐硷拷锟斤拷锟斤拷锟斤拷锟节硷拷锟劫诧拷锟斤拷锟斤拷应锟斤拷使锟矫凤拷锟斤拷锟斤拷每锟斤拷250~500mg锟斤拷始锟斤拷之锟斤拷每锟斤拷锟斤拷锟斤拷500mg锟斤拷直锟斤拷每锟斤拷2.0锟剿ｏ拷锟斤拷锟斤拷效锟斤拷锟斤拷锟皆匡拷锟斤拷锟斤拷每锟斤拷3.0锟剿ｏ拷锟斤拷4锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷效锟斤拷应锟侥憋拷锟斤拷锟狡凤拷锟斤拷锟斤拷锟斤拷要锟斤拷锟斤拷锟斤拷应锟叫讹拷锟侥★拷呕锟铰★拷锟斤拷食锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷痛锟斤拷锟斤拷泻锟斤拷皮锟筋、锟斤拷症状锟斤拷转锟斤拷酶锟斤拷锟竭和匡拷锟斤拷锟皆撅拷锟接硷拷锟劫ｏ拷偶锟叫帮拷细锟斤拷锟斤拷血小锟斤拷锟斤拷伲锟斤拷曰前锟斤拷锟斤拷锟斤拷呓锟斤拷谩锟斤拷锟揭╋拷诩锟接︼拷锟斤拷诓锟窖拷锟斤拷锟酵肝癸拷锟杰★拷
锟斤拷 锟斤拷锟斤拷锟斤拷锟截ｏ拷leflunomide,锟斤拷LEF锟斤拷锟斤拷锟斤拷锟斤拷为10~20mg/锟斤拷锟斤拷锟狡★拷锟斤拷要锟斤拷锟斤拷锟斤拷应锟叫革拷泻锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷血压锟斤拷锟斤拷酶锟斤拷锟竭★拷皮锟筋、锟窖凤拷锟斤拷一锟斤拷锟皆帮拷细锟斤拷锟铰斤拷锟饺ｏ拷锟斤拷药锟斤拷锟斤拷应锟斤拷锟节诧拷喂锟斤拷芎桶锟较革拷锟斤拷锟斤拷锟斤拷锟斤拷禄锟斤拷锟斤拷茫锟斤拷锟斤拷懈锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷睾锟組TX锟斤拷锟斤拷药锟斤拷通锟斤拷锟斤拷同锟斤拷锟斤拷锟斤拷锟斤拷细锟斤拷锟斤拷殖锟斤拷锟绞讹拷锟竭猴拷锟斤拷锟斤拷协同锟斤拷锟矫★拷锟斤拷药锟节硷拷应锟斤拷锟节诧拷血锟斤拷锟斤拷透喂锟斤拷堋锟�
锟斤拷 锟斤拷疟药锟斤拷antimalarials 锟斤拷锟斤拷锟斤拷锟斤拷喹ｏ拷250mg/片锟斤拷锟斤拷锟斤拷锟斤拷喹ｏ拷100mg/片锟斤拷锟斤拷锟街★拷锟斤拷药锟斤拷效锟斤拷锟斤拷锟斤拷锟矫猴拷3~4锟斤拷锟斤拷锟斤拷效锟斤拷叻澹拷锟斤拷锟斤拷锟斤拷锟�6锟斤拷锟铰猴拷锟斤拷锟斤拷锟斤拷锟叫э拷锟斤拷锟叫э拷锟缴硷拷锟斤拷维锟街★拷锟矫凤拷为锟斤拷锟斤拷锟�250mg /锟秸ｏ拷锟斤拷锟斤拷锟�200~400mg /锟秸★拷锟斤拷药锟斤拷锟斤拷锟斤拷锟斤拷茫锟斤拷壮锟斤拷锟斤拷锟斤拷锟斤拷锟侥わ拷锟缴拷锟斤拷锟狡は革拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟侥わ拷锟斤拷远锟斤拷锟绞э拷锟斤拷锟斤拷锟揭╋拷锟斤拷锟斤拷锟斤拷锟接︼拷锟斤拷鄣住锟斤拷锟斤拷猓拷锟街癸拷募锟斤拷鸷Γ锟斤拷锟揭┣帮拷锟接︼拷锟斤拷牡锟酵硷拷锟斤拷锟今挤匡拷峁︼拷懿锟饺拷锟斤拷锟斤拷驶锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷偷锟斤拷锟斤拷嗖★拷锟斤拷锟接︼拷锟斤拷谩锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟接︼拷锟酵凤拷巍锟酵凤拷邸锟狡わ拷睢拷锟斤拷锟斤拷投锟斤拷锟斤拷取锟�
锟斤拷 锟斤拷霉锟斤拷锟斤拷D锟斤拷 penicillamine 锟斤拷锟斤拷250~500mg /锟秸ｏ拷锟节凤拷锟斤拷锟斤拷效锟斤拷锟斤拷鸾ゼ锟斤拷锟轿拷锟斤拷锟�25锟斤拷mg /锟秸★拷锟斤拷霉锟斤拷锟斤拷锟斤拷锟斤拷应锟较多，锟斤拷锟节达拷锟斤拷锟斤拷沙锟斤拷锟斤拷锟斤拷锟�(锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷血锟斤拷锟斤拷锟斤拷锟桔猴拷锟斤拷)锟酵癸拷锟斤拷锟斤拷锟狡等ｏ拷锟界及时停药锟斤拷锟斤拷锟杰恢革拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷应锟叫讹拷锟侥★拷呕锟铰★拷锟斤拷食锟斤拷皮锟筋、锟斤拷腔锟斤拷锟斤拷锟斤拷锟缴ナэ拷锟斤拷馨徒锟斤拷状蟆⒐亟锟酵达拷锟脚硷拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷卟锟斤拷锟斤拷锟斤拷锟街拷锟斤拷锟斤拷锟斤拷锟斤拷喾拷约锟斤拷住锟较低筹拷院锟斤拷锟角达拷锟斤拷锟斤拷锟藉疮锟饺★拷锟斤拷锟斤拷锟节硷拷应锟斤拷锟节诧拷血锟斤拷锟津常癸拷透锟斤拷锟斤拷锟斤拷堋锟�
锟斤拷 锟斤拷诺锟揭ｏ拷auranofin锟斤拷锟斤拷为锟节凤拷锟斤拷锟狡硷拷锟斤拷锟斤拷始锟斤拷锟斤拷为3mg/锟秸ｏ拷2锟杰猴拷锟斤拷锟斤拷6mg/锟斤拷维锟斤拷锟斤拷锟狡★拷锟斤拷锟斤拷锟侥诧拷锟斤拷锟斤拷应锟叫革拷泻锟斤拷锟斤拷锟斤拷锟斤拷皮锟阶★拷锟斤拷锟阶和匡拷锟阶ｏ拷锟斤拷锟斤拷锟叫肝★拷锟斤拷锟斤拷锟剿★拷锟斤拷细锟斤拷锟斤拷锟劫★拷锟斤拷锟斤拷细锟斤拷锟斤拷锟洁、血小锟斤拷锟斤拷倩锟饺革拷锟斤拷锟斤拷佟锟斤拷锟斤拷锟斤拷习锟斤拷锟狡堆拷锟斤拷锟斤拷沙锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷缀锟斤拷圆锟斤拷锟轿拷锟斤拷獠伙拷锟斤拷锟接︼拷锟接︼拷锟斤拷诓锟窖拷虺９婕帮拷巍锟斤拷锟斤拷锟斤拷堋锟斤拷懈锟斤拷锟斤拷锟斤拷锟斤拷诟锟脚拷锟斤拷锟绞癸拷谩锟�
锟斤拷 锟斤拷锟斤拷锟斤拷锟绞ｏ拷azathioprine锟斤拷AZA锟斤拷锟斤拷锟节凤拷锟斤拷50%锟斤拷锟秸★拷锟斤拷锟矫硷拷锟斤拷1~2 mg/锟斤拷锟斤拷/锟秸ｏ拷一锟斤拷100mg/锟秸ｏ拷维锟斤拷锟斤拷为50mg/锟秸★拷锟斤拷锟斤拷锟斤拷应锟斤拷锟窖凤拷锟斤拷皮锟筋，锟斤拷锟斤拷锟斤拷锟狡ｏ拷锟斤拷锟斤拷血小锟斤拷锟斤拷佟锟狡堆拷锟斤拷锟轿革拷锟斤拷锟接︼拷卸锟斤拷摹锟脚伙拷拢锟斤拷锟斤拷懈锟斤拷鸷Γ锟斤拷锟斤拷锟斤拷祝锟斤拷跃锟斤拷印锟斤拷锟斤拷锟斤拷锟揭伙拷锟斤拷锟斤拷耍锟斤拷锟斤拷锟斤拷禄锟斤拷锟斤拷锟斤拷锟接︼拷锟斤拷掳锟斤拷锟斤拷锟揭╋拷诩锟接︼拷锟斤拷诓锟窖拷锟斤拷锟酵肝癸拷锟杰等★拷
锟斤拷 锟斤拷锟斤拷锟截ｏ拷cyclosporin锟斤拷Cs锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟狡硷拷锟斤拷龋锟紺s锟斤拷锟斤拷要锟脚碉拷为锟睫癸拷锟斤拷锟斤拷锟斤拷锟斤拷锟矫ｏ拷锟斤拷锟斤拷锟斤拷症锟斤拷锟绞拷亟锟斤拷住锟斤拷锟斤拷眉锟斤拷锟�3~5mg/锟斤拷锟斤拷/锟秸ｏ拷维锟斤拷锟斤拷锟斤拷2~3mg/锟斤拷锟斤拷/锟秸★拷Cs锟斤拷锟斤拷要锟斤拷锟斤拷锟斤拷应锟叫革拷血压锟斤拷锟斤拷锟斤拷锟斤拷锟皆★拷锟斤拷系统锟金害★拷锟教凤拷锟斤拷染锟斤拷锟斤拷锟斤拷锟皆硷拷胃锟斤拷锟斤拷锟斤拷应锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷毛锟饺★拷锟斤拷锟斤拷锟斤拷应锟斤拷锟斤拷锟截程度★拷锟斤拷锟斤拷时锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷血药浓锟斤拷锟叫关★拷锟斤拷药锟节硷拷应锟斤拷血锟斤拷锟芥、血锟斤拷锟斤拷锟斤拷血压锟饺★拷
锟斤拷 锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷cyclophosphamide锟斤拷CYC锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟绞拷亟锟斤拷祝锟斤拷诙锟斤拷锟揭╋拷锟斤拷锟斤拷锟斤拷锟斤拷曰锟斤拷獠★拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷拢锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷谩锟�
锟斤拷 锟斤拷皮锟绞硷拷锟截ｏ拷锟斤拷
锟斤拷迅锟劫硷拷锟斤拷亟锟斤拷锟酵达拷锟斤拷锟斤拷停锟斤拷诠亟锟斤拷准锟斤拷苑锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟侥★拷锟轿★拷锟桔猴拷锟斤拷系统锟斤拷锟斤拷锟斤拷锟斤拷锟桔碉拷锟斤拷症锟斤拷锟竭ｏ拷锟缴革拷锟斤拷锟叫э拷锟斤拷兀锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟截程度讹拷锟斤拷锟斤拷锟斤拷小锟斤拷锟斤拷锟斤拷皮锟绞硷拷锟截ｏ拷每锟斤拷锟斤拷锟斤拷锟斤拷10mg锟斤拷锟叫э拷锟斤拷锟斤拷锟斤拷兀锟斤拷苫锟斤拷锟斤拷锟斤拷锟斤拷锟竭碉拷症状锟斤拷锟斤拷锟斤拷为DMARDs锟斤拷效前锟侥★拷锟斤拷锟斤拷锟斤拷锟斤拷锟矫ｏ拷锟斤拷NSAIDs锟斤拷效锟斤拷锟斤拷锟斤拷时锟侥讹拷锟节达拷施锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷眉锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷湿锟截斤拷锟阶碉拷锟斤拷锟斤拷锟矫硷拷锟斤拷时应同时锟斤拷锟斤拷DMARDs锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟绞拷亟锟斤拷椎锟皆拷锟斤拷牵锟斤拷锟斤拷锟斤拷么锟斤拷锟斤拷时锟斤拷锟斤拷小锟斤拷锟斤拷锟斤拷锟杰讹拷锟斤拷使锟斤拷锟竭ｏ拷锟斤拷锟斤拷锟斤拷使锟矫ｏ拷锟斤拷锟斤拷锟斤拷锟狡癸拷锟斤拷锟叫ｏ拷注锟解补锟斤拷萍锟斤拷锟轿拷锟斤拷锟斤拷苑锟街癸拷锟斤拷锟斤拷锟斤拷伞锟斤拷亟锟角蛔拷浼わ拷锟斤拷锟斤拷锟斤拷诩锟斤拷锟截斤拷锟斤拷症状锟斤拷锟斤拷锟狡关节癸拷锟杰★拷锟斤拷一锟斤拷锟节诧拷锟剿筹拷锟斤拷3锟轿★拷锟斤拷锟斤拷墓亟锟角伙拷锟斤拷坛锟斤拷瞬锟斤拷锟斤拷锟饺撅拷猓拷锟斤拷煞锟斤拷锟斤拷锟教达拷锟斤拷锟斤拷锟皆关斤拷锟阶★拷
锟斤拷 植锟斤拷药锟狡硷拷锟斤拷
锟斤拷 锟阶癸拷锟劫ｏ拷锟阶癸拷锟劫讹拷甙30~60mg /锟秸ｏ拷锟斤拷3锟轿凤拷锟斤拷锟斤拷锟斤拷锟揭拷锟斤拷锟斤拷锟接︼拷锟斤拷锟斤拷锟斤拷锟斤拷疲锟斤拷锟斤拷戮锟斤拷锟斤拷锟斤拷杉锟斤拷锟斤拷锟斤拷圆锟斤拷锟斤拷锟脚拷员站锟斤拷锟斤拷坠锟斤拷倩锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷刹睢拷锟斤拷摹锟脚伙拷隆锟斤拷锟酵达拷锟斤拷锟叫猴拷龋锟斤拷锟斤拷泄锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷茫锟斤拷锟斤拷锟狡堆拷锟斤拷锟较革拷锟斤拷锟窖★拷锟斤拷锟劫ｏ拷锟斤拷锟叫匡拷锟斤拷锟皆革拷酶锟斤拷锟竭猴拷血锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷陆锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟接︼拷锟斤拷锟狡わ拷睢⑸拷爻锟斤拷拧锟斤拷锟角伙拷锟斤拷锟街革拷妆锟斤拷锟斤拷锟斤拷逊锟斤拷锟斤拷诟伞锟斤拷募隆锟斤拷锟斤拷啤锟酵凤拷邸锟绞э拷叩取锟�
锟斤拷 锟斤拷锟劫碱：锟斤拷锟劫硷拷20mg锟斤拷锟斤拷前锟节凤拷锟斤拷每锟斤拷1~4片锟斤拷每锟斤拷锟斤拷锟轿★拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷应锟斤拷皮锟斤拷锟斤拷锟斤拷锟斤拷皮锟斤拷裙锟斤拷锟斤拷锟接︼拷锟斤拷锟斤拷锟斤拷锟斤拷叱锟斤拷职锟较革拷锟斤拷锟斤拷佟锟�
锟斤拷 锟斤拷锟斤拷锟斤拷甙锟斤拷锟斤拷锟矫硷拷锟斤拷为600mg锟斤拷每锟斤拷2~3锟轿★拷锟斤拷锟斤拷锟斤拷锟斤拷小锟斤拷锟戒不锟斤拷锟斤拷应锟叫达拷锟斤拷锟斤拷锟斤拷锟洁，锟斤拷雀锟酵达拷锟斤拷刹锟饺★拷
2锟斤拷锟斤拷锟斤拷锟斤拷锟�
锟斤拷锟绞拷亟锟斤拷谆锟斤拷呔锟斤拷锟斤拷诳苹锟斤拷锟斤拷锟斤拷锟斤拷药锟斤拷锟斤拷锟狡ｏ拷锟斤拷锟斤拷锟皆诧拷锟杰匡拷锟狡ｏ拷为锟斤拷止锟截节碉拷锟狡伙拷锟斤拷锟斤拷锟斤拷锟斤拷锟轿ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟缴匡拷锟斤拷锟斤拷锟斤拷锟斤拷锟狡★拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟杰革拷锟斤拷锟斤拷锟绞拷亟锟斤拷祝锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷诳锟揭╋拷锟斤拷锟斤拷啤锟斤拷锟斤拷玫锟斤拷锟斤拷锟斤拷锟揭拷谢锟侥わ拷谐锟斤拷锟斤拷锟斤拷亟锟斤拷纬锟斤拷锟斤拷锟斤拷锟斤拷锟街拷山锟斤拷锟睫革拷锟斤拷锟斤拷锟斤拷锟截斤拷锟节猴拷锟斤拷锟斤拷
锟斤拷 锟斤拷膜锟叫筹拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟节ｏ拷锟斤拷锟节硷拷锟斤拷锟节ｏ拷锟斤拷锟竭ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷诳锟斤拷锟斤拷锟斤拷锟斤拷泄亟锟斤拷锟斤拷汀锟斤拷锟酵达拷锟斤拷一锟侥わ拷屎锟絏锟斤拷锟斤拷示锟截斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟街凤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷榷锟斤拷锟斤拷锟斤拷酃亟诒冉暇锟斤拷蓿锟轿拷锟街癸拷亟锟斤拷锟斤拷墙锟揭伙拷锟斤拷苹锟接︼拷锟斤拷腔锟侥わ拷谐锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟绞憋拷锟接︼拷锟斤拷锟斤拷锟斤拷诠亟诰锟斤拷陆锟斤拷谢锟侥わ拷谐锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟叫★拷锟斤拷锟斤拷锟街革拷锟届。锟斤拷膜锟叫筹拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟绞拷锟斤拷锟斤拷锟叫�
锟较好ｏ拷锟斤拷锟斤拷亟锟斤拷锟酵达拷锟斤拷锟斤拷锟斤拷锟斤拷约锟斤拷幔拷锟斤拷芑指锟揭诧拷冉锟斤拷锟斤拷猓拷锟斤拷锟叫э拷锟斤拷锟斤拷锟绞憋拷锟斤拷锟斤拷锟接筹拷锟斤拷锟斤拷锟剿ｏ拷锟斤拷锟街诧拷锟斤拷锟斤拷膜锟斤拷锟斤拷锟斤拷锟斤拷锟劫次诧拷锟斤拷锟皆关斤拷锟斤拷锟角碉拷锟斤拷蚀锟斤拷锟矫★拷锟斤拷耍锟斤拷锟侥わ拷谐锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷诳锟斤拷锟斤拷锟斤拷锟斤拷啤锟�
锟斤拷 锟剿癸拷锟截斤拷锟矫伙拷锟斤拷锟斤拷 锟斤拷一锟斤拷锟斤拷裙亟诨锟斤拷魏突锟斤拷锟街⒆达拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷拧锟较ワ拷亟锟斤拷锟侥壳帮拷俅锟斤拷没锟斤拷锟斤拷墓亟凇锟斤拷锟斤拷锟斤拷锟绞拷锟斤拷锟斤拷系某晒锟斤拷蚀锟�90%锟斤拷锟较★拷锟斤拷锟斤拷锟斤拷锟皆硷拷锟斤拷锟斤拷锟绞拷亟锟斤拷撞锟斤拷洹拷亟锟斤拷锟酵达拷锟斤拷锟斤拷巍锟斤拷锟斤拷锟斤拷习锟斤拷锟斤拷锟斤拷锟斤拷粘锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟绞拷锟斤拷锟饺凤拷锟斤拷锟斤拷锟斤拷锟斤拷茫锟斤拷乇锟斤拷嵌锟斤拷锟斤拷锟斤拷凇锟斤拷亟锟斤拷锟斤拷锟斤拷苹锟斤拷锟斤拷锟斤拷锟斤拷锟酵达拷锟斤拷锟斤拷巍锟斤拷锟斤拷锟斤拷习锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟侥伙拷锟斤拷锟斤拷为锟斤拷效锟斤拷锟解、锟襟及硷拷亟锟轿拷歉锟斤拷毓亟冢锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷通锟斤拷锟斤拷膜锟叫筹拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟皆硷拷锟斤拷锟斤拷锟斤拷锟截斤拷之锟斤拷锟斤拷硕锟斤拷锟斤拷锟斤拷锟斤拷锟揭伙拷锟斤拷锟斤拷锟斤拷锟矫关斤拷锟矫伙拷锟斤拷锟斤拷
锟斤拷 锟斤拷锟斤拷锟斤拷锟斤拷织锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟绞拷亟锟斤拷壮锟斤拷斯锟斤拷曰锟斤拷魏凸亟锟斤拷锟秸筹拷锟斤拷锟斤拷锟缴的关节伙拷锟斤拷锟解，锟截斤拷锟揭猴拷锟斤拷围锟侥硷拷锟解、锟斤拷锟斤拷锟轿拷锟揭诧拷锟斤拷锟缴关节伙拷锟轿碉拷原锟斤拷之一锟斤拷锟斤拷耍锟轿拷私锟斤拷锟截斤拷锟揭猴拷锟斤拷围锟斤拷锟解、锟斤拷锟斤拷锟轿拷锟斤拷锟斤拷佣锟斤拷锏斤拷锟斤拷锟斤拷亟诨锟斤拷蔚锟侥匡拷模锟斤拷锟斤拷锟斤拷锟斤拷锟街拷山锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷亟锟斤拷野锟斤拷锟斤拷锟斤拷锟斤拷亟锟斤拷锟斤拷锌锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷山锟斤拷锟接筹拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷些锟斤拷锟斤拷锟斤拷同时锟斤拷锟叫ｏ拷锟绞可筹拷之为锟截斤拷锟缴斤拷锟斤拷锟斤拷锟斤拷锟叫硷拷锟斤拷锟斤拷锟斤拷锟斤拷锟街诧拷应锟斤拷锟斤拷惴猴拷锟斤拷诮锟斤拷锟斤拷斯锟斤拷亟锟斤拷没锟绞憋拷锟斤拷锟斤拷锟揭拷锟斤拷锟斤拷锟斤拷锟街拷山锟侥凤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟轿★拷锟斤拷锟斤拷织锟缴斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟脚关斤拷锟斤拷锟秸伙拷锟斤拷时锟斤拷锟叫讹拷锟斤拷锟秸硷拷锟斤拷锟皆革拷锟狡关节活动锟斤拷锟斤拷锟斤拷锟斤拷锟秸伙拷锟轿ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷某些锟斤拷锟斤拷锟斤拷锟斤拷锟绞拷亟锟斤拷谆锟斤拷呋锟斤拷蔚锟斤拷锟斤拷诮锟斤拷锟斤拷锟斤拷锟斤拷锟桔猴拷证锟洁常锟斤拷锟斤拷锟斤拷锟斤拷痛锟斤拷锌锟斤拷锟窖癸拷锟斤拷锟斤拷锟斤拷锟斤拷准锟斤拷锟斤拷锟斤拷湿锟截斤拷锟阶的肩、锟脚关节等达拷锟斤拷锟界经锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷效锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟叫筹拷锟斤拷锟絅锟斤拷锟斤拷锟阶较筹拷锟斤拷锟节革拷锟斤拷膝锟截斤拷锟阶ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷锟绞拷亟锟斤拷祝锟皆拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷偶锟斤拷锟斤拷锟斤拷锟斤拷锟狡★拷锟斤拷锟绞拷锟斤拷一锟斤拷锟斤拷诩锟斤拷锟斤拷幕疃拷冢锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷谐锟斤拷锟街伙拷薪锟节较达拷锟斤拷锟斤拷痛症状锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷效锟竭ｏ拷锟斤拷锟斤拷锟斤拷锟叫筹拷锟斤拷
锟斤拷 锟截斤拷锟节猴拷锟斤拷锟斤拷锟斤拷锟斤拷锟剿癸拷锟截斤拷锟矫伙拷锟斤拷锟侥成癸拷应锟矫ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷锟截斤拷锟节猴拷锟斤拷锟窖猴拷锟斤拷使锟矫ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷锟节关斤拷锟阶伙拷锟竭★拷锟截斤拷锟狡伙拷锟斤拷锟截★拷锟截节诧拷锟饺的匡拷锟叫关斤拷锟节猴拷锟斤拷锟斤拷锟斤拷锟解，锟截斤拷锟节猴拷锟斤拷锟斤拷锟斤拷锟斤拷为锟截斤拷锟矫伙拷锟斤拷锟斤拷失锟杰碉拷锟斤拷锟斤拷锟斤拷锟斤拷锟�
3锟斤拷锟斤拷锟斤拷锟酵匡拷锟斤拷锟斤拷锟斤拷
锟截斤拷锟斤拷痛锟斤拷锟斤拷锟铰残废伙拷锟窖撅拷锟斤拷圆蟹稀锟斤拷锟斤拷畈伙拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟绞э拷锟斤拷锟酵ワ拷锟斤拷锟斤拷训裙锟较碉拷谋洹拷缃伙拷锟斤拷只疃拷锟酵Ｖ癸拷锟斤拷锟斤拷锟斤拷锟截诧拷锟缴憋拷锟斤拷母锟斤拷锟斤拷湿锟截斤拷锟阶伙拷锟竭达拷锟斤拷锟斤拷锟斤拷压锟斤拷锟斤拷锟斤拷锟角匡拷锟斤拷锟斤拷锟狡ｏ拷却锟街碉拷锟斤拷药锟斤不锟斤拷锟斤拷应锟斤拷锟揭╋拷锟绞碉拷锟斤拷锟斤拷锟叫э拷锟斤拷锟斤拷牟锟斤拷悖拷锟斤拷旨锟斤拷锟斤拷嘶锟斤拷叩锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷湿锟截斤拷锟阶伙拷锟斤拷锟斤拷锟筋常锟斤拷锟侥撅拷锟斤拷症状锟斤拷锟斤拷锟截碉拷锟斤拷锟斤拷锟叫帮拷锟斤拷锟斤拷锟侥恢革拷锟斤拷锟斤拷耍锟斤拷诨锟斤拷锟斤拷锟斤拷锟斤拷锟揭╋拷锟斤拷锟斤拷锟酵憋拷锟斤拷锟接ψ拷锟斤拷锟斤拷湿锟截斤拷锟阶碉拷锟斤拷锟斤拷锟斤拷锟狡★拷锟斤拷锟解，锟斤拷锟斤拷锟狡凤拷锟斤拷锟斤拷选锟斤拷锟斤拷锟叫э拷锟斤拷锟斤拷锟斤拷锟接︼拷锟较伙拷锟竭撅拷锟斤拷症状锟侥改变。锟斤拷锟节硷拷锟斤拷锟节关节撅拷锟斤拷锟斤拷痛锟酵帮拷锟斤拷全锟斤拷症状锟斤拷应锟皆达拷锟斤拷息锟斤拷锟斤拷注锟斤拷锟斤拷息时锟斤拷锟斤拷位锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷亟锟斤拷锟窖癸拷锟轿拷锟斤拷止亟诠锟斤拷锟轿伙拷锟斤拷锟揭憋拷锟斤拷诩邪锟教讹拷锟斤拷2-3锟杰ｏ拷锟斤拷锟皆凤拷锟斤拷锟轿★拷锟节诧拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷拢锟斤拷锟斤拷斜锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷墓亟诨疃拷锟窖碉拷锟斤拷锟斤拷锟街癸拷锟轿拷锟斤拷锟斤拷曰锟斤拷锟斤拷诨锟斤拷撸锟斤拷诓锟绞癸拷锟斤拷吒械锟狡ｏ拷偷锟角帮拷锟斤拷拢锟斤拷锟斤拷锟斤拷锟剿讹拷锟斤拷锟斤拷 锟斤拷锟街革拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷医师指锟斤拷锟铰斤拷锟斤拷锟斤拷锟狡★拷
4锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷
锟斤拷锟斤拷锟狡硷拷锟界抗TNF-锟斤拷锟斤拷锟斤拷细锟斤拷锟斤拷植锟斤拷锟斤拷锟狡凤拷锟窖匡拷始锟斤拷锟斤拷锟斤拷锟绞拷亟锟斤拷椎锟斤拷锟斤拷疲锟斤拷锟饺凤拷锟斤拷锟叫э拷筒锟斤拷锟斤拷锟接︼拷锟斤拷锟斤拷锟斤拷嗖★拷锟斤拷某锟斤拷诠鄄锟斤拷锟斤拷铩�
锟斤拷锟斤拷锟狡诧拷锟皆ｏ拷
锟节碉拷锟斤拷锟斤拷锟绞拷亟锟斤拷撞锟斤拷鼙锟斤拷锟斤拷蔚锟斤拷锟斤拷锟铰ｏ拷锟斤拷止锟截斤拷锟狡伙拷锟斤拷锟斤拷锟斤拷锟截节癸拷锟杰ｏ拷锟斤拷锟斤拷薅鹊锟斤拷锟竭伙拷锟竭碉拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟角碉拷锟斤拷锟侥匡拷辏拷锟剿ｏ拷锟斤拷锟斤拷时锟斤拷锟角筹拷锟斤拷要锟斤拷锟斤拷锟节伙拷锟斤拷锟斤拷锟斤拷锟斤拷使锟斤拷DMARDs锟斤拷锟斤拷锟角硷拷锟斤拷锟铰残的关硷拷 锟斤拷锟斤拷锟杰ｏ拷 NSAIDs锟斤拷锟斤拷皮锟绞硷拷锟截匡拷锟皆硷拷锟斤拷症状锟斤拷锟斤拷锟截斤拷锟斤拷症锟斤拷锟狡伙拷锟皆可凤拷锟斤拷锟斤拷锟秸癸拷锟斤拷锟斤拷械锟紻MARDs锟叫匡拷锟杰硷拷锟斤拷锟斤拷止锟截斤拷锟狡伙拷锟斤拷锟斤拷锟矫★拷锟斤拷锟斤拷锟斤拷锟绞拷亟锟斤拷椎锟皆拷锟斤拷锟窖革拷俑锟斤拷锟絅SAIDs锟斤拷锟斤拷锟斤拷痛锟斤拷锟斤拷症锟斤拷锟斤拷锟斤拷使锟斤拷DMARDs锟斤拷锟皆硷拷锟劫伙拷锟接伙拷锟斤拷锟狡伙拷锟斤拷锟斤拷锟斤拷指锟斤拷锟斤拷药锟斤拷锟窖★拷锟揭拷锟斤拷习锟饺拷锟斤拷锟叫э拷锟斤拷锟斤拷煤图锟斤拷原锟斤拷锟斤拷锟绞拷亟锟斤拷谆锟斤拷锟揭伙拷锟斤拷锟较硷拷锟斤拷始DMARDs锟斤拷锟狡★拷锟狡硷拷锟斤拷选锟斤拷锟矫碉拷锟斤拷装锟斤拷锟斤拷剩锟組TX锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷啶★拷锟斤拷锟斤拷喹★拷锟接诧拷锟斤拷傻锟斤拷锟揭诧拷刹锟斤拷锟斤拷锟斤拷只锟斤拷锟斤拷锟斤拷锟斤拷系锟紻MARDs锟斤拷锟斤拷锟斤拷锟狡★拷一锟斤拷缘锟斤拷锟揭伙拷锟紻MARDs锟斤拷效锟斤拷锟矫ｏ拷锟斤拷锟秸癸拷浴锟皆わ拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷湿锟截斤拷锟阶伙拷锟竭可诧拷锟矫伙拷锟斤拷锟斤拷同锟斤拷DMARDs锟斤拷锟斤拷锟斤拷锟狡★拷锟斤拷锟斤拷锟斤拷药时锟斤拷锟戒不锟斤拷锟斤拷应锟斤拷一锟斤拷锟饺碉拷一锟斤拷药锟洁。锟斤拷锟斤拷锟斤拷药时锟斤拷锟斤拷锟绞碉拷锟斤拷锟斤拷锟斤拷锟斤拷每锟斤拷药锟斤拷募锟斤拷锟斤拷锟斤拷锟組TX锟斤拷选锟斤拷7.5mg锟斤拷25mg/锟杰猴拷锟斤拷锟斤拷锟斤拷锟斤拷锟�1.0~3.0g/锟秸★拷目前锟斤拷锟矫碉拷锟斤拷锟较凤拷锟斤拷锟叫ｏ拷
锟斤拷 MTX+锟斤拷锟斤拷锟斤拷锟斤拷啶ｏ拷
锟斤拷 MTX+锟斤拷锟斤拷喹ｏ拷锟斤拷锟斤拷喹ｏ拷锟斤拷锟斤拷 MTX+锟斤拷霉锟斤拷锟斤拷锟斤拷 MTX+锟斤拷诺锟揭ｏ拷锟斤拷 MTX+锟斤拷锟斤拷锟斤拷锟绞ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟�+锟斤拷锟斤拷喹ｏ拷锟斤拷锟节伙拷锟缴诧拷锟斤拷MTX锟斤拷植锟斤拷药(锟斤拷锟阶癸拷锟劫★拷锟斤拷锟劫硷拷桶锟斤拷锟斤拷锟竭�)锟斤拷锟斤拷锟斤拷锟狡★拷锟界患锟竭讹拷MTX锟斤拷锟斤拷锟斤拷锟杰ｏ拷锟缴革拷锟斤拷锟斤拷锟斤拷锟斤拷锟截伙拷锟斤拷锟斤拷DMARDs锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟绞拷亟锟斤拷卓锟斤拷锟組TX+锟斤拷锟斤拷锟斤拷锟截伙拷锟斤拷锟紻MARDs锟斤拷锟斤拷锟斤拷锟狡★拷锟斤拷锟斤拷锟劫达拷强锟斤拷指锟斤拷锟斤拷锟斤拷锟斤拷选锟斤拷锟斤拷一锟斤拷锟斤拷锟狡凤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷前锟斤拷锟斤拷锟斤拷双锟街ｏ拷锟斤拷锟斤拷锟斤拷亟冢锟絏锟斤拷锟斤拷锟斤拷锟斤拷酃亟诘亩猿锟斤拷锟絏锟斤拷锟洁，锟斤拷锟斤拷锟斤拷锟狡猴拷锟斤拷锟疥复锟斤拷X锟斤拷锟斤拷锟斤拷锟皆比斤拷锟斤拷效锟斤拷为锟斤拷锟斤拷药锟斤不锟斤拷锟斤拷应锟斤拷锟斤拷药锟斤拷锟斤拷锟斤拷应锟斤拷锟杰观诧拷血锟津常规、锟斤拷锟斤拷锟斤拷锟杰诧拷锟斤拷时锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟狡凤拷应锟斤拷锟饺斤拷锟斤拷锟斤拷前锟斤拷墓亟锟窖雇达拷锟斤拷锟斤拷统潭群凸亟锟斤拷锟斤拷锟斤拷锟斤拷酃亟诜锟斤拷锟窖э拷谋锟斤拷猓拷锟接︼拷锟斤拷锟斤拷锟斤拷锟阶刺拷锟斤拷锟斤拷郏锟揭斤拷锟斤拷突锟斤拷叨约锟斤拷锟斤拷疃拷缘锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷邸锟斤拷锟斤拷锟斤拷谢锟斤拷叨锟接︼拷锟解病锟斤拷幕疃拷浴锟斤拷锟斤拷锟斤拷凇锟斤拷锟斤拷锟斤拷诨锟斤拷锟斤拷锟斤拷锟筋动锟侥伙拷锟斤拷应锟斤拷锟斤拷锟斤拷锟斤拷锟�,直锟斤拷锟斤拷锟斤拷锟斤拷啤锟斤拷锟斤拷诨锟斤拷锟斤拷诘幕锟斤拷呖锟斤拷锟矫匡拷锟斤拷锟斤拷锟斤拷一锟轿ｏ拷同时锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷药锟斤拷锟揭拷锟斤拷诨锟斤拷锟斤拷锟接χ革拷辍Ｓ︼拷锟斤拷锟饺凤拷锟斤拷锟斤拷锟斤拷坪锟斤拷症状锟斤拷锟解，锟斤拷锟斤拷锟节硷拷锟斤拷锟侥革拷锟轿ｏ拷锟斤拷锟斤拷锟斤拷效锟斤拷锟斤拷锟斤拷远锟斤拷锟斤拷效锟斤拷DMARDs锟斤拷锟斤拷锟接伙拷锟斤拷锟斤拷锟秸癸拷锟斤拷锟斤拷嗖伙拷锟斤拷锟斤拷锟斤拷锟斤拷湿锟截斤拷锟阶ｏ拷锟斤拷锟斤拷锟斤拷一锟姐，为锟斤拷止锟斤拷锟介复锟斤拷原锟斤拷锟较诧拷停药锟斤拷锟斤拷也锟斤拷锟斤拷锟捷诧拷锟斤拷锟金渐硷拷锟斤拷维锟斤拷锟斤拷锟斤拷,直锟斤拷锟斤拷锟斤拷停锟矫★拷锟斤拷锟斤拷锟斤拷锟斤拷湿锟截斤拷锟阶伙拷锟竭诧拷锟斤拷迁锟接ｏ拷锟斤拷锟绞拷亟锟斤拷锟酵�2~3锟斤拷锟斤拷虏锟斤拷式细撸锟斤拷绮伙拷锟斤拷锟斤拷锟斤拷锟斤拷锟狡ｏ拷3锟斤拷锟节关斤拷锟狡伙拷锟斤拷70%锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷确锟斤拷锟斤拷锟狡匡拷使80%锟斤拷锟较碉拷锟斤拷锟绞拷亟锟斤拷谆锟斤拷卟锟斤拷榛猴拷猓伙拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷虏小锟�
目前锟斤拷锟斤拷准确预锟斤拷预锟斤拷锟街革拷辏拷锟斤拷锟轿拷锟斤拷锟斤拷员锟脚拷锟皆わ拷锟矫ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟竭较凤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷预锟斤拷茫锟斤拷锟绞憋拷亟锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷趾锟截斤拷锟斤拷锟桔★拷锟津病筹拷锟斤拷锟桔硷拷锟截斤拷锟斤拷锟斤拷锟斤拷20锟斤拷预锟斤拷睿伙拷锟斤拷锟斤拷叩味锟斤拷锟斤拷湿锟斤拷锟斤拷锟斤拷锟皆★拷锟斤拷锟斤拷血锟斤拷锟斤拷锟介、C锟斤拷应锟斤拷锟斤拷锟斤拷锟竭★拷血锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷细锟斤拷锟斤拷锟斤拷锟斤拷锟绞驹わ拷锟筋；锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷症状锟斤拷锟斤拷锟饺★拷贫血锟斤拷锟斤拷锟斤拷锟斤拷锟酵关斤拷锟斤拷锟斤拷郑锟斤拷锟斤拷湿锟斤拷凇锟斤拷锟侥わ拷住锟斤拷锟斤拷锟斤拷苑尾锟斤拷锟斤拷陌锟斤拷锟斤拷锟斤拷锟较低筹拷锟窖拷锟斤拷椎锟斤拷锟斤拷锟斤拷锟斤拷耍锟皆わ拷锟斤拷锟斤拷锟斤拷锟斤拷诩锟斤拷锟斤拷锟斤拷锟街⒆达拷锟斤拷钥锟斤拷苹锟斤拷锟轿拷旨锟斤拷锟斤拷锟斤拷芗锟斤拷锟�10mg/锟斤拷锟斤拷锟斤拷锟斤拷预锟斤拷睢�
锟斤拷锟斤拷 |
